Actions Requested of Healthcare Providers
- SUSPECT shigellosis in patients with compatible symptoms.
- TEST by obtaining stool cultures and antimicrobial susceptibility testing. PCR testing does not replace stool culture.
- Consider testing stool specimens with rapid enteric panel PCR testing followed by reflex cultures for bacterial enteritis, as may be necessary in some settings.
- Test shigellosis patients for HIV and STIs (particularly syphilis), as co-infections are common. Substance use disorders may present as co-morbidities.
- TREAT appropriately, considering local resistance patterns and individual susceptibility results.
- Empiric antibiotic treatment with fluoroquinolones (Ciprofloxacin or Levofloxacin). Based on recently isolated samples, this strain of Shigella sonnei is susceptible only to Ciprofloxacin and Levofloxacin (fluoroquinolones) and resistant to Ampicillin, Ceftriaxone, and Trimethoprim-Sulfamethoxazole.
- Subsequently tailor antibiotic treatment when individual susceptibility results are available.
- REPORT suspected and confirmed shigellosis cases to the Communicable Disease Unit:
- Call 831-454-4114 or submit a Confidential Morbidity Report (CMR) by faxing 831-454-5049 or via the CalREDIE Provider Portal.
- It is especially important to report cases in sensitive occupations and situations (i.e. food handlers, direct care givers in health care facilities or group settings, or persons attending daycare, etc.). Cases in sensitive situations should be excluded from these settings while symptomatic and until Public Health restrictions are lifted.
- COUNSEL patients on hand hygiene practices and avoiding activities while symptomatic that could pose.
- As per general guidance for enteric illnesses such as Shigella/Shigellosis, we recommend that patients wait 48 hours without diarrhea before resuming use of shared living spaces. Symptomatic sheltered persons should be provided separate sleeping accommodations and dedicated restroom facilities, whenever possible, and all symptomatic persons should be provided testing for Shigella and other enteric pathogens, including norovirus.
Provider Resources
Health Alerts:
Disease Reporting Information: www.santacruzhealth.org/CDUnit
Centers for Disease Control (CDC) Shigellosis Treatment Guidance: www.cdc.gov/shigella/audience-medical-professionals.html